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Effects of GSH on the mRNA levels of pro-infammatory cytokines in LPS-induced MH7A cells and mouse SFs The TNF-α, IL-6, and IL-10 are implicated in the pathogenesis of RA.[12] To investigate the effects of GSH and determine its appropriate dose on LPS-induced pro-inflammatory cytokine production, mouse SFs were pretreated with different concentrations of GSH ranging from 50 to 150 μg/mL with or without LPS for 24 h